Applications of PCR Laboratories

PCR Laboratories, also known as gene amplification laboratories, have witnessed significant advancements in DNA quantification technology with real-time fluorescence quantitative PCR. This specialized technique amplifies specific DNA fragments, serving as a DNA replication process outside living organisms. We provide high-quality PCR consumables including PCR Plates, PCR Tubes, and more.

Through DNA gene tracking systems, rapid assessment of viral loads within patients' bodies can be achieved with nanometer-level precision. Real-time fluorescence quantitative PCR serves as the carrier for this technology. PCR assays commonly detect viral infectious diseases such as HIV/AIDS, hepatitis B, and avian influenza, determining whether individuals with low viral loads harbor specific viruses.

PCR detection methods offer high sensitivity, specificity, rapidity, and minimal sample requirements, widely accepted by clinicians. Extensively utilized in clinical diagnostics within hospitals and epidemic prevention departments, particularly for avian influenza diagnosis.

Driven by national policies and pandemic developments, hospitals at all levels across regions establish compliant PCR laboratories, a standard requirement for healthcare institutions. However, some nucleic acid laboratories in low-risk areas remain inactive aside from emergency functions, posing concerns for hospital leadership regarding substantial investments without generating revenue.

Despite powerful capabilities, PCR laboratories primarily focus on qualitative analysis and quantitative detection. Besides COVID-19 nucleic acid testing, these versatile laboratories can achieve much more, illustrated through specific application directions across various medical systems.

Pathogen Determination:

PCR technology enables rapid detection of pathogens, addressing issues related to immunological testing "window periods" and distinguishing between current and past infections.

Example: Novel Coronavirus Nucleic Acid Detection.

Methodology: Fluorescence PCR.

Purpose: Qualitative detection of suspected pneumonia cases caused by the novel coronavirus, aiding diagnosis or differentiation of infection.

Genetic Disease Testing:

Real-time PCR technology detects gene mutations and variations, addressing challenges in clinical testing for genetic diseases.

Example: Detection of Microdeletions in the AZF Region of the Human Y Chromosome.

Methodology: Fluorescence PCR.

Purpose: Diagnosing male infertility by detecting microdeletions in the Y chromosome AZF region.

Personalized Medication:

Pharmacogenomics guides personalized medication, detecting genetic variations in drug metabolism to develop rational drug treatment plans.

Example: Cardiovascular Personalized Medication Guidance Testing.

Methodology: Fluorescence PCR.

Purpose: Providing personalized medication recommendations based on genetic typing for commonly used cardiovascular drugs.

Tumor Research:

PCR methodologies detect oncogenes, tumor suppressor genes, and gene methylation, aiding in tumor diagnosis and prognosis assessment.

Sample Types: Whole blood/tissue.